Browsing Department of Chemistry (CHM) by Author "Otuokere, I.E"
Now showing items 1-4 of 4
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Computational Study on Molecular Orbital’s, Excited State Properties and Geometry Optimization of Anti-benign Prostatic Hyperplasia Drug, N- (1,1-dimethylethyl)-3-oxo-(5α,17β)-4-azaandrost-1-ene-17-carboxamide (Finasteride).
Otuokere, I.E; Alisa, C. O. (Asian Journal of Research in Pharmaceutical Science, 2014)Finasteride, N-(1,1-dimethylethyl)-3-oxo-(5α, 17β)-4-azaandrost-1-ene-17-carboxamide is a synthetic drug for the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB). The electronic excited-st ... -
Electronic and Fourier Transform Infrared Spectroscopic Characterization of Dicomponent Antimalarial drugs sold in Nigeria Drug Stores
Otuokere, I.E; Alisa, C.O; Jonah, C.O (Research Journal of Pharmaceutical Dosage Forms and Technology, 2015-06)Dicomponent antimalarial drugs were purchased from different drug stores in Nigeria. The electronic and vibrational spectra characterization of these drugs was carried out. The electronic spectra of these drugs showed that ... -
Molecular Mechanics Steric Energy Evaluation of Reversible Acetyl cholinesterase Inhibitor, Donepezil, (RS)-2-([1-benzyl-4-piperidyl] methyl)-5,6-dimethoxy-2,3-dihydroinden-1-one
Otuokere, I.E; Alisa, C.O. (Indian Journal of Advances in Chemical Science, 2014)Donepezil, (RS)-2-[(1-benzyl-4-piperidyl) methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one is a specific and reversible inhibitor of acetyl cholinesterase, for the symptomatic treatment of Alzheimer’s disease and vascular ... -
Synthesis, Characterization and Complexation Behaviour of Chloroquine towards Ti (II) Ion Using Chloroquine Diphosphate Drug
Otuokere, I.E; Okpara, L.O; Amadi, K.C; Alisa, C.O; Okoyeagu, A; Nwadire, F.C (Journal of Pharmaceutical Research International, 2019-06-01)Aims: Chloroquine is a member of the drug class 4-aminoquinoline used for the prevention and treatment of malaria in areas where malaria is known to be sensitive to its effects. Our aim is to synthesize the chloroquine ...